Why the study?
Are serum levels of soluble adhesion molecules elevated in patients with Type 2 diabetes mellitus, and do they correlate with glycaemic control?
Are serum levels of soluble adhesion molecules elevated in patients with Type 2 diabetes mellitus, and do they correlate with glycaemic control?
Soluble adhesion molecules are elevated in Type 2 diabetes independently of glycaemic control, suggesting alternative mechanisms like concurrent hypertension or hypercholesterolaemia drive endothelial dysfunction.
No takes yet. Share an insight, caveat, or question.
Should not yet change glycaemic targets in T2DM; hypothesis-generating for hypertension or lipids driving endothelial activation.
Steiner et al. (1994) studied this question.