Why the study?
Does the choice of primary anesthetic agent (enflurane, halothane, isoflurane, or sufentanil) reduce postoperative myocardial infarction or death in patients undergoing coronary artery bypass grafting?
Population
1,012 patients undergoing coronary artery bypass grafting (CABG) operations
Comparison
Primary anesthetic agent: enflurane, halothane… vs Active comparators
Design
RCT, prospectively randomized
Authors
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Choice of primary anesthetic does not affect post-CABG MI or death; confirms hemodynamic control as the anesthesiologist's dominant priority.
Does the choice of primary anesthetic agent (enflurane, halothane, isoflurane, or sufentanil) reduce postoperative myocardial infarction or death in patients undergoing coronary artery bypass grafting?
The choice of primary anesthetic agent during CABG does not significantly impact the incidence of postoperative MI or death, highlighting that heart rate control is the primary role of the anesthesiologist.
Slogoff et al. (1989) studied this question.