Real-World Effectiveness of Rotavirus Vaccine against Rotavirus Disease among Children 2 Year of Age in Mali

Key Points

• The aim is to estimate the effectiveness of the rotavirus vaccine among children under two years old in Mali.
• Test-negative case-control design used to evaluate vaccine effectiveness from 2015-2018.
• Population included children under 2 years of age.
• Assessment of vaccine impact on rotavirus disease burden.
• Rotavirus vaccine was found to be 60% effective, with a 95% confidence interval of 3%-84%.
• Findings suggest a significant reduction in rotavirus disease among vaccinated children.
• The effectiveness highlights the vaccine's role in addressing health challenges in Mali.