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April 27, 2026Open Access

Pitfalls and difficulties in histological diagnosis of human dirofilariasis due to Dirofilaria (Nochtiella) repens

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Authors

PSPampiglione SCGCanestri Trotti G.FRFrancesco RivasiUniversity of Modena and Reggio Emilia

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Implication

Histologic study explores diagnostic difficulties in Dirofilaria repens infections, suggesting improved techniques for diagnosis.

Key Points

  • The study aims to identify the diagnostic pitfalls in histological examination of Dirofilaria repens infections.
  • Conducted a histologic study of over 90 cases of Dirofilaria repens infection.
  • Illustrated difficulties in diagnosis due to regressive phenomena affecting parasite morphology.
  • Recommended diverse sectioning of nodules to enhance identification of preserved features.
  • Highlighted that death of the filaria before surgical removal leads to diagnostic challenges.
  • Described examples of histologic sections showcasing varying degrees of structural preservation.
  • Identified critical morphologic features necessary for accurate diagnosis.

Cite This Study

S et al. (1999) studied this question.

synapsesocial.com/papers/69eefd82fede9185760d4391https://doi.org/10.1016/s0732-8893(98)00164-1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Not a Dead-End Host: First Confirmed Persistent Microfilaremia in Human Dirofilaria repens Infection2025 · 2 citations
  2. 2Abdominal Subcutaneous Dirofilariasis Due to Dirofilaria repens in a 34-Year-Old Sicilian Woman: Diagnostic Challenges and Molecular Confirmation2025
  3. 3Unmasking the Unknown2026
  4. 4Subcutaneous Dirofilariasis of the Lateral Cervical Region: A Case Report2025
  5. 5Integrated imaging in rare eyelid lesions: a case report of palpebral dirofilariosis2025