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April 1, 2026Alzheimer s & DementiaOpen Access

Differential associations between traumatic brain injury severity and four dementia phenotypes in military veterans

Victoria C. Merritt Elizabeth Valocchi Francesca V. Lopez Georgios Asimakopoulos Alexandra L. Clark Lay Kodama Amy J. Jak Lu Liu Catherine Chanfreau‐Coffinier

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Key Points

The aim is to assess how different severities of traumatic brain injury (TBI) relate to various dementia phenotypes in military veterans.
Analyzed relationships between TBI severity and dementia phenotypes in military veterans.
Examined associations to evaluate the dose-response relationship.
Identified a dose-response relationship between TBI severity and dementia risk.
Raised questions regarding the association between TBI and Alzheimer's disease (AD) specifically.

Implication

Findings show associations between TBI severity and dementia phenotypes in military veterans, suggesting potential risks.

Abstract

Findings support a dose-response relationship between TBI severity and broader dementia risk but raise questions regarding the TBI-AD link.

Discussion

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Cite This Study

Merritt et al. (2026) studied this question.

synapsesocial.com/papers/69eefdb5fede9185760d47ed https://doi.org/10.1002/alz.71370

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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