What question did this study set out to answer?

To investigate the incidence of stroke, Parkinson disease, epilepsy, and dementia in older Veterans before and after acute TBI.

June 20, 2026Neurology

Neurologic Diagnoses Before and After Traumatic Brain Injury

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To investigate the incidence of stroke, Parkinson disease, epilepsy, and dementia in older Veterans before and after acute TBI.
Identified Veterans aged ≥55 years with acute TBI using VHA databases.
Matched participants 3:1 with a non-TBI cohort based on demographics.
Calculated incidence rate ratios (IRRs) comparing pre-TBI and post-TBI periods.
Veterans with TBI had significantly higher pre-TBI incidence rates of stroke (IRR = 3.2), dementia (IRR = 3.1), PD (IRR = 3.0), and epilepsy (IRR = 4.4) compared to the non-TBI cohort.
Post-TBI, incidence rates also increased for stroke (IRR = 1.83) and epilepsy (IRR = 2.29), with dementia incidence higher (IRR = 1.24), while PD rates remained stable (IRR = 1.06).

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Retrospective cohort study investigating neurologic conditions before and after TBI in older Veterans, suggesting a bidirectional association.

Peltz et al. (2026) studied this question.

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Retrospective cohort study investigating neurologic conditions before and after TBI in older Veterans, suggesting a bidirectional association.