What question did this study set out to answer?

This study aimed to determine the prevalence and clinical implications of ischemic hepatitis in patients with decompensated heart failure presenting to the emergency department.

April 27, 2026Düzce Tıp Fakültesi DergisiOpen Access

Frequency of Ischemic Hepatitis in Patients Presenting to the Emergency Department with a Diagnosis of Decompensated Heart Failure and Clinical Outcomes of Patients with Ischemic Hepatitis

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HSHasan SultanoğluSağlık Bilimleri Üniversitesi

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Implication

Retrospective study investigates ischemic hepatitis prevalence and clinical outcomes in emergency department patients, indicating significant mortality risks.

Key Points

This study aimed to determine the prevalence and clinical implications of ischemic hepatitis in patients with decompensated heart failure presenting to the emergency department.
Retrospective analysis of adult patients aged ≥18 years with NYHA class III-IV decompensated heart failure from January 2020 to January 2024.
Ischemic hepatitis was defined by a ≥10-fold elevation of AST and/or ALT after excluding other causes.
Clinical and laboratory data compared between patients with and without ischemic hepatitis.
11.9% of patients (45 out of 378) developed ischemic hepatitis.
IH (+) patients exhibited significantly lower blood pressures and higher heart rates, with elevated AST, ALT, INR, bilirubin, troponin, and creatinine levels (all p<0.001).
ICU admission rates were significantly higher in IH (+) patients (75.6% vs. 21.6%), with in-hospital mortality rates also higher (35.6% vs. 6.0%) (p<0.001).

Cite This Study

Hasan Sultanoğlu (2026) studied this question.

synapsesocial.com/papers/69eefe1efede9185760d4d1e https://doi.org/10.18678/dtfd.1768790

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Implication

Retrospective study investigates ischemic hepatitis prevalence and clinical outcomes in emergency department patients, indicating significant mortality risks.

Frequency of Ischemic Hepatitis in Patients Presenting to the Emergency Department with a Diagnosis of Decompensated Heart Failure and Clinical Outcomes of Patients with Ischemic Hepatitis

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Cite This Study

Frequency of Ischemic Hepatitis in Patients Presenting to the Emergency Department with a Diagnosis of Decompensated Heart Failure and Clinical Outcomes of Patients with Ischemic Hepatitis

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Cite This Study

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