Why the study?
Can routine urine samples be used for adherence testing screening by LC-MS/MS to detect nonadherence to cardiovascular medications in people with T2DM?
Can routine urine samples be used for adherence testing screening by LC-MS/MS to detect nonadherence to cardiovascular medications in people with T2DM?
Biochemical urine testing using LC-MS/MS is a feasible method to detect high rates of cardiovascular medication nonadherence, particularly to statins, in patients with Type 2 diabetes.
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Supports LC-MS/MS urine testing for nonadherence screening in T2DM; hypothesis-generating and should not yet change practice.
This unique study shows that routine urine samples can be used for adherence testing screening by LC-MS/MS and has demonstrated high nonadherence rates especially to statins in people with T2DM. Future intervention studies using LC-MS/MS as a diagnostic/therapeutic tool may help to improve clinical outcomes.
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Patel et al. (2019) studied this question.
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