Capability and accuracy of usual statistical analyses in a real-world setting using a federated approach

Our project showed a practical implementation and use case of a real-world federated approach using DataSHIELD. The capability and accuracy of common data manipulation and analysis were satisfying, and the flexibility of the tool enabled the production of a variety of analyses while preserving the privacy of individual data. The DataSHIELD forum was also a practical source of information and support. In order to find the right balance between privacy and accuracy of the analysis, set-up of privacy requirements should be established prior to the start of the analysis, as well as a data quality review of the participating healthcare organization.