Do DOACs reduce the incidence of dementia compared to VKAs in patients with atrial fibrillation?
DOACs are associated with a reduced risk of dementia compared to VKAs in patients with atrial fibrillation, especially in younger patients and for vascular dementia.
This meta-analysis reveals a reduction in incidence of dementia in AF patients prescribed DOACs compared to VKA, particularly in those less than 75 years old and in the vascular dementia subtype.
Chokesuwattanaskul et al. (Wed,) studied this question.