Characterization of Cardiac Sympathetic Nervous System and Inflammatory Activation in HFpEF Patients

Figures

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  Figure 1. Systemic and Cardiac Sympathetic Activity in HFpEF Bar graphs showing the plasma arterial concentration of norepinephrine (NE) and the transcardiac NE plasma concentration gradient and related metabolites dihydroxyphenylglycol (DHPG) and dihydyroxyphenylalanine (DOPA) in healthy subjects and heart failure with preserved ejection fraction (HFpEF) patients.

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  Figure 2. Physiologic Correlates of Sympathetic Activity in HFpEF Scatterplots showing the correlations between hemodynamic parameters and plasma arterial concentration of NE and the transcardiac NE plasma concentration gradient healthy subjects and HFpEF patients. PCWP= pulmonary capillary wedge pressure; other abbreviations as in Figure 1.

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  Figure 3. Systemic and Myocardial Cytokine Profiles in HFpEF (A,B) Principal component analysis plots of the profile of plasma arterial concentrations of inflammatory cytokines and of their transcardiac concentration gradients in healthy subjects and HFpEF patients.