Does the extent of coronary collaterals determine the development of intramyocardial hemorrhage in revascularized STEMI patients?
Coronary collateral status may help identify revascularized STEMI patients at high risk for intramyocardial hemorrhage and subsequent infarct expansion.
Extent of coronary collaterals is a determinant of IMH in revascularized STEMI. Since IMH is known to drive post-PCI infarct expansion, determination of collateral status has the potential to identify patients at high risk of infarct expansion. For these high-risk patients, novel targeted therapies to reduce IMH, limit post-MI infarct expansion, and improve outcomes should be further explored.
Vora et al. (Sat,) studied this question.