Why the study?
Do circulating biomarkers of collagen synthesis accurately reflect myocardial collagen content in patients with hypertrophic cardiomyopathy?
Population
Patients with hypertrophic cardiomyopathy (HCM)
Design
Other
Authors
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Caution against relying on peripheral collagen biomarkers for myocardial fibrosis in HCM; leaves open need for direct tissue assessment.
Do circulating biomarkers of collagen synthesis accurately reflect myocardial collagen content in patients with hypertrophic cardiomyopathy?
Peripheral circulating biomarkers of collagen synthesis are not useful for estimating myocardial collagen content in patients with hypertrophic cardiomyopathy.
Ellims et al. (2014) studied this question.
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