Why the study?
Does Cardiac Resynchronization Therapy provide benefit in patients depending on QRS duration?
Does Cardiac Resynchronization Therapy provide benefit in patients depending on QRS duration?
CRT provides significant benefit in patients with QRS ≥ 150 ms, but not in those with QRS < 150 ms.
CRT indicated for QRS ≥150 ms; reinforces guideline threshold for patient selection.
The benefit of CRT seems to be dependent on QRS duration. Available data suggest a significant benefit associated with CRT in patients with QRS ≥ 150 ms, but not in patients with QRS < 150 ms. Further studies are needed to identify patients with QRS < 150 ms who might benefit from CRT.
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Stavrakis et al. (2011) studied this question.
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