Why the study?
Does amlodipine reduce plasma IL-6 levels in patients with congestive heart failure?
Does amlodipine reduce plasma IL-6 levels in patients with congestive heart failure?
Amlodipine reduces plasma IL-6 levels in patients with congestive heart failure, suggesting a potential cytokine-mediated mechanism for its clinical effects.
Supports amlodipine consideration in inflammatory CHF; extends mechanistic evidence beyond hemodynamics in this RCT.
Amlodipine lowers plasma IL-6 levels in patients with CHF. The beneficial effect of amlodipine in CHF may be due to a reduction of cytokines such as IL-6.
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Mohler et al. (1997) studied this question.
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