Why the study?
Does impaired coronary flow reserve modify the effect of elevated troponin on major adverse cardiovascular events in patients without overt coronary artery disease?
Does impaired coronary flow reserve modify the effect of elevated troponin on major adverse cardiovascular events in patients without overt coronary artery disease?
In patients without overt CAD, impaired coronary flow reserve (reflecting microvascular dysfunction) is associated with elevated troponin and modifies its effect on major adverse cardiovascular events.
In patients without overt CAD, impaired CFR was independently associated with minimally elevated troponin and major adverse cardiovascular events. Impaired CFR, here reflecting microvascular dysfunction, modified the effect of a positive troponin on adverse outcomes.
No takes yet. Share an insight, caveat, or question.
Taqueti et al. (2014) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: