Do different flow-gradient patterns of aortic stenosis affect clinical outcomes after aortic valve replacement?
Following aortic valve replacement, patients with classical low-flow, low-gradient aortic stenosis have worse 2-year outcomes compared to those with high-gradient AS, while those with low-gradient AS and preserved LVEF have comparable outcomes.
The LG AS pattern was highly prevalent (36.5%) in the PARTNER 2 trial and registry. CLF-LG was the most common pattern of LG AS and was associated with higher rates of death, rehospitalization, or stroke at 2 years compared with the HG group. Clinical outcomes were as good in the LG AS groups with preserved left ventricular ejection fraction compared with the HG group.
Salaün et al. (Wed,) studied this question.