Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
March 16, 2020HeartOpen Access

Role of advanced left ventricular imaging in adults with aortic stenosis

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Ejection fraction is currently the only LV parameter recommended to guide intervention in AS, but the 50% cut-off is debated and advanced LV imaging may help optimise the timing of aortic valve replacement.

Does advanced left ventricular imaging improve risk stratification and optimize the timing of aortic valve replacement in adults with aortic stenosis?

Population

Adults with aortic stenosis

Design

Review

Authors

ACAndreea CălinEcolab (United Kingdom)AMA. MateescuCarol Davila University of Medicine and PharmacyAPAndreea C. PopescuUniversity of Bucharest

Discussion

Loading...

Member takes

Overview

Should not yet guide AVR timing in asymptomatic severe AS; leaves open whether GLS or LGE improves risk stratification in randomized trials.

Structured PICO

Does advanced left ventricular imaging improve risk stratification and optimize the timing of aortic valve replacement in adults with aortic stenosis?

P
Population
Adults with aortic stenosis, particularly asymptomatic patients with severe aortic stenosis and preserved left ventricular ejection fraction
I
Intervention
Advanced left ventricular imaging (global longitudinal LV strain by speckle tracking echocardiography, cardiac magnetic resonance for myocardial fibrosis)
O
Outcome
Prediction of disease progression and clinical outcomes to optimize timing of aortic valve replacement

Advanced LV imaging techniques like speckle tracking echocardiography and CMR show promise for risk stratification in asymptomatic severe aortic stenosis, but require validation in randomized trials before routine clinical implementation.

Limitations

  • Lack of convincing data for T1 mapping in aortic stenosis
  • Data from randomized clinical trials are awaited to define utility in daily practice

Cite This Study

Călin et al. (2020) studied this question.

synapsesocial.com/papers/69effa62bce9831ba4f73b30https://doi.org/10.1136/heartjnl-2019-315211
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Myocardial deformation in aortic valve stenosis: relation to left ventricular geometry2009 · 135 citations
  2. 2Relationship Between Left Ventricular Ejection Fraction and Mortality in Asymptomatic and Minimally Symptomatic Patients With Severe Aortic Stenosis2018 · 112 citations
  3. 3Progression From Compensated Hypertrophy to Failure in the Pressure-Overloaded Human Heart2003 · 1,112 citations
  4. 4Predictors of Mortality and Outcomes of Therapy in Low-Flow Severe Aortic Stenosis2013 · 416 citations
  5. 5Left Ventricular Hypertrophy With Strain and Aortic Stenosis2014 · 134 citations