Does cardiovascular magnetic resonance identifying specific phenotypic features predict the presence of sarcomere gene mutations in subclinical hypertrophic cardiomyopathy?
Specific CMR findings, including crypts and anterior mitral valve leaflet elongation, can help identify sarcomere gene mutations in subclinical hypertrophic cardiomyopathy.
The subclinical hypertrophic cardiomyopathy phenotype measured by cardiovascular magnetic resonance in a multicenter environment and consisting of crypts (particularly multiple), anterior mitral valve leaflet elongation, abnormal trabeculae, and smaller LV systolic cavity is indicative of the presence of sarcomere gene mutations and highlights the need for further study.
Captur et al. (Wed,) studied this question.