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Lower frontal lobe perfusion linked to lower systolic blood pressure is associated with depressive symptoms in older adults, suggesting a potential therapeutic target for preventing incident depression.
This study demonstrates that lower frontal lobe perfusion, related to lower values of baseline systolic blood pressure, is associated with clinically significant depressive symptoms in a cohort of community-dwelling older people. Given the recognised longitudinal association between lower blood pressure and depression in older people, this may represent a potential therapeutic target for prevention of incident depression.Declaration of interestNone.
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Briggs et al. (2019) studied this question.
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