Why the study?
Does surgical aortic valve replacement improve diastolic function, and is diastolic dysfunction a marker for long-term survival in patients with aortic stenosis?
Does surgical aortic valve replacement improve diastolic function, and is diastolic dysfunction a marker for long-term survival in patients with aortic stenosis?
Diastolic dysfunction may not be a reliable marker for poor long-term survival after SAVR, whereas high preoperative NT-proBNP and PHF are associated with increased mortality.
Diastolic dysfunction should not yet inform post-SAVR prognosis; leaves open validation of NT-proBNP and PHF as mortality markers.
Surgery for aortic stenosis improved diastolic function in patients with high LV filling pressure in 50% of the patients. Our results could not confirm the previously suggested role of diastolic dysfunction as a marker for poor long-term survival after SAVR. Our findings showed that both PHF and high preoperative NT-proBNP were associated with long-term mortality.
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Hultkvist et al. (2022) studied this question.
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