Why the study?
Does aortic valve replacement improve left ventricular diastolic function and reduce hypertrophy in patients with isolated aortic stenosis?
Population
41 patients with isolated aortic stenosis and normal systolic function
Design
Cohort
Follow-up
four years
Authors
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AVR may support sustained LV remodeling in isolated AS; extends short-term data but leaves open randomized outcome trials.
Does aortic valve replacement improve left ventricular diastolic function and reduce hypertrophy in patients with isolated aortic stenosis?
Aortic valve replacement for isolated aortic stenosis leads to early and sustained improvements in left ventricular diastolic function and regression of left ventricular hypertrophy over four years.
Ignatios Ikonomidis (2001) studied this question.
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