Key result
Valve replacement for aortic stenosis yielded long-term maintenance of NYHA class I in 75% of patients who were preoperatively class II, compared to only 23% of those in class IV (P<0.05).
Why the study?
Does preoperative status predict late functional status and left ventricular performance after valve replacement for aortic stenosis?
Population
Patients who underwent valve replacement for aortic stenosis between 1965 and 1973.
Design
Cohort
Follow-up
10-17 years (mean 12 years)
Authors
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Preoperative NYHA class predicts long-term functional status after aortic valve replacement; leaves open whether earlier intervention improves outcomes in contemporary cohorts.
Cohort
Does preoperative status predict late functional status and left ventricular performance after valve replacement for aortic stenosis?
p-value: p=<0.05
Functional status and left ventricular performance late after aortic valve replacement depend closely on preoperative status, suggesting that earlier surgical intervention in minimally symptomatic patients may yield better long-term outcomes.
Lund et al. (1988) conducted a cohort in Aortic stenosis. Valve replacement vs. Preoperative NYHA class (II vs III vs IV) was evaluated on Maintenance of NYHA class I at 10 years (p=<0.05). Valve replacement for aortic stenosis yielded long-term maintenance of NYHA class I in 75% of patients who were preoperatively class II, compared to only 23% of those in class IV (P<0.05).
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