Age and gender effects on arterial stiffness differ between local (carotid) and central measurements in healthy middle-aged individuals, which must be considered when designing or interpreting arterial stiffness studies.
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Site-specific age-gender effects on stiffness warrant caution in measurement choice; leaves open optimal central parameter for middle-aged cohorts.
The relation with age and gender of local and central stiffness measures is not the same over the age range 35-55 in apparently healthy men and women. Depending on the central stiffness parameter used, age-gender effects evident at the carotid artery are or are not found centrally. Though the relevance of these differences requires further evaluation in a longitudinal study with outcome data, they need to be kept in mind when designing or interpreting results from arterial stiffness evaluation studies.
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Vermeersch et al. (2008) studied this question.
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