April 25, 2013European Heart Journal170 citationsOpen Access

Vascular lesions induced by renal nerve ablation as assessed by optical coherence tomography: pre- and post-procedural comparison with the Simplicity® catheter system and the EnligHTN™ multi-electrode renal denervation catheter

CTChristian TemplinInterventional Cardiology MJMiłosz JaguszewskiInterventional Cardiology JGJelena R. GhadriCardiac Imaging

Structured PICO

Does optical coherence tomography identify vascular lesions induced by renal nerve ablation that are not apparent on angiography?

Population

Patients undergoing renal nerve ablation

Intervention

Renal nerve ablation (RNA) using the Simplicity catheter system or the EnligHTN multi-electrode renal denervation catheter, assessed by optical coherence tomography (OCT)

Comparator

Pre-procedural state and standard angiography

Outcome

Vascular lesions (diffuse renal artery constriction, local tissue damage, oedema, and thrombus formation)safety

OCT reveals significant vascular damage and thrombus formation following renal nerve ablation that is missed by standard angiography, suggesting a potential need for dual antiplatelet therapy during the procedure.

Abstract

Here we show that diffuse renal artery constriction and local tissue damage at the ablation site with oedema and thrombus formation occur after RNA and that OCT visualizes vascular lesions not apparent on angiography. This suggests that dual antiplatelet therapy may be required during RNA.

问 AI

Bookmark

View Full Paper