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August 31, 1995New England Journal of Medicine

Efficacy of Metformin in Patients with Non-Insulin-Dependent Diabetes Mellitus

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Authors

RDRalph A. DeFronzoDartmouth CollegeAGA. GoodmanAssociation for Children at Risk

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DeFronzo et al. (1995) studied this question.

synapsesocial.com/papers/69effb1eafa91c76b5d0a764https://doi.org/10.1056/nejm199508313330902
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Treating insulin resistance in hypertension with metformin reduces both blood pressure and metabolic risk factors1991 · 225 citations
  2. 2Effect of Metformin on Insulin-Stimulated Glucose Turnover and Insulin Binding to Receptors in Type II Diabetes1987 · 109 citations
  3. 3Retinopathy in Older Type II Diabetics Association With Glucose Control1986 · 132 citations
  4. 4Pathogenesis of NIDDM: A Balanced Overview1992 · 2,097 citations