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Substantial mortality in moderate/severe AS with LVSD warrants optimized strategies; leaves open transcatheter AVR utility pending further study.
In patients with moderate/severe AS and LVSD, mortality is substantial and amongst those selected for surgery, AVR with or without CABG is associated with higher survival. Research is required to understand factors contributing to current practice patterns and the possible utility of transcatheter approaches in this high-risk cohort.
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Samad et al. (2016) studied this question.
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