Pregnancy-Associated Plasma Protein A and Its Endogenous Inhibitor, the Proform of Eosinophil Major Basic Protein (proMBP), Are Related to Complex Stenosis Morphology in Patients With Stable Angina Pectoris

Juan Cosı́n-Sales; Michael Christiansen; Paul F. Kaminski; Claus Oxvig; Michael T. Overgaard; Della Cole; David W. Holt; Juan Carlos Kaski

doi:10.1161/01.cir.0000124716.67921.d2

March 16, 2004CirculationOpen Access

Pregnancy-Associated Plasma Protein A and Its Endogenous Inhibitor, the Proform of Eosinophil Major Basic Protein (proMBP), Are Related to Complex Stenosis Morphology in Patients With Stable Angina Pectoris

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Why the study?

Are PAPP-A and PAPP-A/proMBP ratio associated with angiographic plaque complexity in patients with stable angina pectoris?

Structured PICO

Are PAPP-A and PAPP-A/proMBP ratio associated with angiographic plaque complexity in patients with stable angina pectoris?

P

Population

Patients with stable angina pectoris

I

Intervention

Pregnancy-Associated Plasma Protein A (PAPP-A) and PAPP-A/proMBP ratio levels

O

Outcome

Angiographic plaque complexity / complex stenosis morphologysurrogate

PAPP-A and the PAPP-A/proMBP ratio are associated with angiographic plaque complexity in patients with stable angina.

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Implication

PAPP-A may mark plaque complexity in stable angina; hypothesis-generating and should not change practice without prospective validation.

Abstract

In patients with stable angina, PAPP-A and PAPP-A/proMBP ratio are associated with angiographic plaque complexity.

Discussion

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Cite This Study

Cosı́n-Sales et al. (2004) studied this question.

synapsesocial.com/papers/69effb624f6a06657c21e405 https://doi.org/10.1161/01.cir.0000124716.67921.d2

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Pregnancy-Associated Plasma Protein A and Its Endogenous Inhibitor, the Proform of Eosinophil Major Basic Protein (proMBP), Are Related to Complex Stenosis Morphology in Patients With Stable Angina Pectoris

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Pregnancy-Associated Plasma Protein A and Its Endogenous Inhibitor, the Proform of Eosinophil Major Basic Protein (proMBP), Are Related to Complex Stenosis Morphology in Patients With Stable Angina Pectoris

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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