Do Direct Oral Anticoagulants (DOACs) reduce the risk of dementia compared to warfarin in an Asian population with atrial fibrillation?
In an Asian population with atrial fibrillation, DOACs have a comparable overall risk of dementia to warfarin, though edoxaban may offer a lower risk.
In this large Asian population with atrial fibrillation, DOAC showed a comparable risk of dementia with warfarin overall. DOACs appeared more beneficial than warfarin, in those aged 65 to 74 years or with a history of stroke. For specific DOACs, only edoxaban was associated with a lower risk of dementia than warfarin.
Lee et al. (Thu,) studied this question.