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This research aims to address the underdiagnosis and undertreatment of women with wild-type transthyretin cardiac amyloidosis (ATTRwt-CM).

April 28, 2026European Heart Journal - Quality of Care and Clinical Outcomes0 citations

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Tafamidis in women with wild-type transthyretin cardiac amyloidosis: an international cohort study

PDPhilippe Debonnaire WLW L'hoyes KDKarl Dujardin

Key Points

This research aims to address the underdiagnosis and undertreatment of women with wild-type transthyretin cardiac amyloidosis (ATTRwt-CM).
Cohort study design
Focus on women with ATTRwt-CM
Assessment of treatment efficacy and natural disease progression
Women with ATTRwt-CM have similar poor outcomes as men despite effective tafamidis treatment.
There is an urgent need for initiatives to improve diagnostic awareness and treatment for these women.

Abstract

Women with ATTRwt-CM are prone to underdiagnosis and undertreatment, despite similar poor natural course and tafamidis treatment efficacy. Initiatives to increase diagnostic awareness and disease modifying treatment initiation in women are urgently needed.

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Tafamidis in women with wild-type transthyretin cardiac amyloidosis: an international cohort study

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