Recovery of renal function and structure following AKI is a complex and multifactorial process involving coordinated tubular epithelial regeneration, resolution of inflammation, restoration of microvascular integrity, and remodeling of the extracellular matrix. Clinical recovery is variable and influenced by injury severity, comorbidities, and therapeutic interventions. Advances in biomarkers and imaging techniques enhance early prediction and monitoring of recovery trajectories. Although no definitive therapies currently exist to reliably speed recovery, promising approaches, including stem cell secretome administration and growth factor modulation, are in development. Long-term consequences of incomplete structural repair highlight the importance of sustained patient follow-up after apparent recovery from AKI.
Ahim et al. (Thu,) studied this question.