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December 2, 2025˜The œNephron journals/Nephron journals

Discovery Pipeline for AKI: Molecules, Mechanisms, Models, and Targets

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Authors

TCTanima ChatterjeeJRJoseph RutkowskiDSDanielle E Soranno

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Overview

This analysis reveals novel therapeutic targets in acute kidney injury, suggesting roles of ferroptosis and cholinergic pathways in disease progression.

Key Points

  • Acute kidney injury leads to significant loss of kidney function, impacting overall health and increasing risks of chronic disease.
  • Discussion identifies the role of ferroptosis in kidney injury, highlighting its importance in treatment strategies.
  • Assessment examining novel therapeutic targets and ion channels, investigating potential pathways for intervention.
  • Implications underline how understanding molecular networks can reshape approaches to managing kidney disease effectively.

Cite This Study

Chatterjee et al. (2025) studied this question.

synapsesocial.com/papers/692e3da16c9b3ab28c187bb5https://doi.org/10.1159/000549795
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