Prospective longitudinal observational study evaluates cone structure and retinal function in laser-induced retinopathy, indicating structural recovery.
Key Points
This study aims to assess structural changes in photoreceptors and lesion remodeling during recovery from laser-induced retinopathy.
Prospective longitudinal observational design with 13 patients and 15 eyes.
Employs AO-SLO, OCT, and microperimetry for baseline and 6-month follow-up assessments.
Evaluates lesion area, cone metrics, and retinal sensitivity.
Lesion area significantly decreased from 97,128 µm² to 27,560 µm² (P = 0.031).
Perilesional cone density increased from 27,942 to 36,700 cones/mm² (P = 0.010).
Retinal sensitivity improved from 19.25 dB to 26.43 dB (P < 0.001).