Why the study?
Does a three-layered appearance on intravascular ultrasound correlate with intimal thickening in normal coronary arteries?
Population
16 intact hearts excised at autopsy from patients with no clinical history of coronary artery disease, ages…
Comparison
Intravascular ultrasound imaging of epicardial… vs Histological analysis of corresponding sections
Design
Cross-sectional
Authors
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May flag early intimal changes on IVUS; leaves open prognostic value in normal coronaries.
Does a three-layered appearance on intravascular ultrasound correlate with intimal thickening in normal coronary arteries?
A three-layered appearance on intravascular ultrasound of normal coronary arteries indicates intimal thickening of at least 178 microns and is more common with advancing age.
Fitzgerald et al. (1992) studied this question.
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