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May 26, 2011Heart

Genetics and cardiovascular disease—causes and prevention of unexpected sudden adult death: the role of the SADS clinic

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Population

First-degree relatives of patients with sudden arrhythmic death syndrome (SADS)

Design

Review

Authors

LNLaurence NunnMaidstone and Tunbridge Wells NHS TrustPLPier D. LambiaseElectrophysiology

Discussion

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Implication

Supports SADS family screening; leaves open standardized protocols and prospective outcome data.

Structured PICO

P
Population
First-degree relatives of patients with sudden arrhythmic death syndrome (SADS)
I
Intervention
Clinical screening and molecular autopsy

This review highlights the importance of clinical screening and molecular autopsy in first-degree relatives of SADS patients to identify inherited conditions and prevent further sudden deaths.

Cite This Study

Nunn et al. (2011) studied this question.

synapsesocial.com/papers/69f14b762811130d0cde21afhttps://doi.org/10.1136/hrt.2010.218511
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Molecular Diagnosis of the Inherited Long-QT Syndrome in a Woman Who Died after Near-Drowning1999 · 147 citations
  2. 2National service framework for coronary heart disease2000 · 833 citations
  3. 3The circadian pattern of the development of ventricular fibrillation in patients with Brugada syndrome1999 · 334 citations
  4. 4The Idiopathic Long QT Syndrome: Pathogenetic Mechanisms and Therapy1985 · 150 citations
  5. 5Molecular autopsy in sudden cardiac death and its implication for families: discussion of the practical, legal and ethical aspects of the multidisciplinary collaboration2009 · 43 citations