Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 1, 1975Journal of Biological ChemistryOpen Access

Interactions between actin, myosin, and an actin-binding protein from rabbit alveolar macrophages. Alveolar macrophage myosin Mg-2+-adenosine triphosphatase requires a cofactor for activation by actin.

View Full Paper
Ask AI
Bookmark
Share

Population

Purified proteins from rabbit alveolar macrophages and rabbit skeletal muscle

Comparison

Addition of a partially purified cofactor from… vs Absence of the cofactor

Design

Preclinical

Authors

TSThomas P. StosselLinköping UniversityJHJohn H. HartwigLinköping University

Discussion

Loading...

Member takes

Implication

Rabbit macrophage myosin requires cofactor for F-actin ATPase activation; leaves open analogous regulation in human cardiovascular cells.

Structured PICO

P
Population
Purified proteins (actin, myosin, actin-binding protein) from rabbit alveolar macrophages and rabbit skeletal muscle
I
Intervention
Addition of a partially purified cofactor from macrophage extracts
C
Comparator
Absence of the cofactor
O
Outcome
Mg2+ATPase activitysurrogate

Rabbit alveolar macrophage myosin requires a cofactor for activation of its Mg2+ATPase activity by F-actin, with no evidence for calcium ion participation in regulating this activity.

Cite This Study

Stossel et al. (1975) studied this question.

synapsesocial.com/papers/69f14bebc0d8017361865b46https://doi.org/10.1016/s0021-9258(19)41236-2
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1COBALT AS A MITOCHONDRIAL DENSITY MARKER IN A STUDY OF CYTOPLASMIC EXCHANGE DURING MATING OF SCHIZOPHYLLUM COMMUNE1973 · 10 citations
  2. 2Electron Microscopic Identification of Actin Associated with Isolated Amoeba Plasma Membranes1973 · 138 citations
  3. 3Microfibrils of blood platelets: their relationship to microtubules and the contractile protein1969 · 100 citations