Fractional Flow Reserve in Patients With Prior Myocardial Infarction
Why the study?
Does a fractional flow reserve cutoff of 0.75 accurately detect flow maldistribution on SPECT imaging in patients with prior myocardial infarction?
Population
57 patients who had sustained a myocardial infarction ≥6 days earlier
Comparison
Fractional flow reserve measurement using a 0.75… vs Myocardial perfusion single photon emission…
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Supports 0.75 FFR cutoff for ischemia detection post-MI; leaves open viable myocardium effects in prospective studies.
Structured PICO
Does a fractional flow reserve cutoff of 0.75 accurately detect flow maldistribution on SPECT imaging in patients with prior myocardial infarction?
P
Population
57 patients who had sustained a myocardial infarction ≥6 days earlier
I
Intervention
Fractional flow reserve (FFR) measurement using a 0.75 cutoff value
C
Comparator
Myocardial perfusion single photon emission scintigraphy (SPECT) imaging (reference standard)
O
Outcome
Sensitivity, specificity, and concordance of FFR to detect flow maldistribution at SPECT imagingsurrogate
An FFR cutoff of 0.75 remains a valid threshold for detecting ischemia in patients with prior myocardial infarction, though the FFR value is influenced by the mass of viable myocardium.
Cite This Study
Bruyne et al. (2001) studied this question.