World Heart Federation Cholesterol Roadmap 2022
Authors
Discussion
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Implication
Expert consensus review reveals life-course cholesterol management strategies in global populations, highlighting early intervention to curb atherosclerotic cardiovascular disease.
Key Points
- To provide an updated framework and identify actionable health system strategies to overcome barriers in cholesterol control and prevent atherosclerotic cardiovascular disease worldwide.
- Reviewed international clinical guidelines and cardiovascular research published since 2017.
- Convened an expert committee on dyslipidemia clinical management and health systems research in low- and middle-income countries to identify knowledge-practice gaps and system roadblocks.
- Identified the critical need to transition clinical risk stratification from 10-year risk calculators to lifetime risk models addressing cumulative exposure to apolipoprotein B.
- Advocated for universal screening for inherited dyslipidemias, wider accessibility of affordable cholesterol testing, and global inclusion of potent statins as essential medicines.
- Recommended combination regimens using statins and ezetimibe to achieve target LDL-cholesterol reductions, supported by improved health literacy and multidisciplinary care teams.
Cite This Study
Ray et al. (2022) studied this question.