Pilot cohort study finds biliary drainage improves survival rates in patients with mushroom poisoning, suggesting a new therapeutic strategy.
Amatoxin-containing mushroom poisoning causes fatal acute liver failure with >50% mortality despite maximal medical therapy. Interrupting the enterohepatic recirculation of amatoxins is a mechanistically rational but unproven therapeutic strategy. This study aimed to evaluate the efficacy and safety of biliary drainage (BD) in patients with pre-liver failure caused by amatoxin-containing mushroom poisoning.
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Ma et al. (2026) studied this question.
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