Bioinspired Total Synthesis of (Dibromo)Sceptrin and (Dibromo)Ageliferin

Mohammed Latrache; Amina Sesay; Mireia Benito Montaner; Samuel Oger; Mellah Mohamed; Erwan Poupon; Stephen Timothy Hilton; Stellios Arseniyadis; Laurent Evanno

doi:10.1039/d6cc01851c

January 1, 2026Chemical CommunicationsOpen Access

Bioinspired Total Synthesis of (Dibromo)Sceptrin and (Dibromo)Ageliferin

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Key Points

The research aims to develop a bioinspired method for synthesizing marine alkaloids.
Traditional synthesis techniques were replaced with bioinspired approaches.
Photocatalytic dimerization was employed in the synthesis process.
The study focused on the synthesis of sceptrin, dibromosceptrin, ageliferin, and dibromoageliferin.
Successfully synthesized marine alkaloids using bioinspired methodologies.
Demonstrated the effectiveness of photocatalytic dimerization in producing alkaloids.

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Implication

Bioinspired synthesis produces marine alkaloids sceptrin and ageliferin, suggesting new synthetic pathways.

Abstract

We report a bioinspired synthesis of the emblematic marine alkaloids sceptrin, dibromosceptrin, ageliferin and dibromoageliferin. Central to this approach is a photocatalytic dimerization of fully elaborated precursors via [2+2] or...

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Latrache et al. (2026) studied this question.

synapsesocial.com/papers/69f154a4879cb923c4944d23 https://doi.org/10.1039/d6cc01851c

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Bioinspired Total Synthesis of (Dibromo)Sceptrin and (Dibromo)Ageliferin

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Bioinspired Total Synthesis of (Dibromo)Sceptrin and (Dibromo)Ageliferin

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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