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April 24, 2026Critical Care ExplorationsOpen Access

The Vigilance Gradient: Nine Years of Adverse Event Trends in Pediatric Critical Care

Devika Singh Michael R. Miller Maitray A. Patel Cory Anderson Douglas D. Fraser

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Key Points

This research aims to investigate trends in adverse events and assess the impact of the COVID-19 pandemic on pediatric critical care.
Retrospective cohort study design
Analyzed data over 11 years in a single-center pediatric critical care unit
Used interrupted time series analyses and mixed-effects multinomial regression
AE rates increased by 5.20 events per 100 cases at pandemic onset
Post-pandemic, AE rates rose again by 1.94 events per 100 cases quarterly
Higher Pediatric Index of Mortality 2 scores were associated with more severe adverse events

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Implication

Retrospective cohort study reveals increased adverse events in pediatric critical care, suggesting stronger monitoring is needed post-COVID.

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Cite This Study

Singh et al. (2026) studied this question.

synapsesocial.com/papers/69f154e0879cb923c4945171 https://doi.org/10.1097/cce.0000000000001407

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