Why the study?
Does immunoadsorption improve left ventricular ejection fraction in patients with idiopathic dilated cardiomyopathy and beta(1)-adrenoceptor autoantibodies?
Population
34 patients with idiopathic dilated cardiomyopathy, moderate to severe heart failure, and evidence of…
Comparison
Immunoadsorption added to standard medical therapy vs Standard medical therapy alone
Design
Case-control
Follow-up
1 year
Authors
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Immunoadsorption was associated with LVEF improvement in autoantibody-positive DCM; hypothesis-generating, needs randomized confirmation before practice change.
Does immunoadsorption improve left ventricular ejection fraction in patients with idiopathic dilated cardiomyopathy and beta(1)-adrenoceptor autoantibodies?
Immunoadsorption added to standard medical therapy significantly improves left ventricular ejection fraction and clinical status in patients with idiopathic dilated cardiomyopathy and beta(1)-adrenoceptor autoantibodies.
Müller et al. (2000) studied this question.
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