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This research aims to develop and evaluate the cytotoxicity of bacterial cellulose and hydroxylated hexagonal boron nitride nanocomposites.

April 29, 2026MRS BulletinOpen Access

Biofabrication of bacterial cellulose and hydroxylated hexagonal boron nitride nanocomposites based on in situ production strategies: Characterization and cytotoxicity evaluation

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Randomized trial evaluates cell response to bacterial cellulose and boron nitride nanocomposites, suggesting promising biomedical applications.

This research aims to develop and evaluate the cytotoxicity of bacterial cellulose and hydroxylated hexagonal boron nitride nanocomposites.
In situ fermentation method was used to produce hydroxylated hexagonal boron nitride modified bacterial cellulose nanocomposites.
Physicochemical properties and cell responses were characterized using Fourier transform infrared spectroscopy, x-ray diffraction, and various microscopy techniques.
Cell viability, adhesion, and proliferation were assessed through MTT assays and microscopy methods.
BC/BN nanocomposites significantly promoted cell viability and adhesion compared to bacterial cellulose alone.
Enhanced osteoblast cell proliferation was observed with higher cell viability rates noted for the BC/BN composites.

Semra Ünal (2026) studied this question.

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Randomized trial evaluates cell response to bacterial cellulose and boron nitride nanocomposites, suggesting promising biomedical applications.