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Community-based surveys measure mpox seroprevalence in urban and rural groups, indicating potential outbreak spread.
Background This study aimed to assess mpox seroprevalence in South-Kivu, DRC, where a large mpox outbreak started at the end of 2023. Methods We conducted community-based surveys in urban (April–May 2023) and rural (July–August 2024) areas and used a multiplex serological assay to detect anti-IgG against mpox. Results Mpox seroprevalence was 3.3% in the urban survey (n=1,174) and 8.3% in the rural survey (n=981), with differences according to health zone (p=0.004) after the mpox outbreak. Conclusion This study shows temporal and geographic variation in MPXV seroprevalence and suggest potential spread of mpox in the general population in South-Kivu.
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Nkuba-Ndaye et al. (2026) studied this question.
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