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April 29, 2026European Journal of Ophthalmology

Optical coherence tomography measurements in retinopathy of prematurity: A systematic review and meta-analysis

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Authors

SJSayena JabbehdariSFSepehr FekrazadMassachusetts Eye and Ear InfirmaryAOAnthony OganovStony Brook University Hospital

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Implication

Systematic review and meta-analysis reveal persistent macular changes in individuals with retinopathy of prematurity, suggesting implications for clinical practices.

Key Points

  • To evaluate the effectiveness of optical coherence tomography (OCT) measurements in detecting macular changes in individuals with retinopathy of prematurity (ROP).
  • Conducted a systematic review and meta-analysis of optical coherence tomography studies related to retinopathy of prematurity.
  • Assessed layer-specific and region-specific macular alterations in individuals with prior ROP.
  • Analyzed methodological heterogeneity impacting the applicability of thickness-based biomarkers.
  • Individuals with prior ROP show persistent macular alterations linked to disrupted neurovascular development.
  • Considerable variability exists among OCT platforms and geographic locations, affecting results.
  • Methodological differences limit the use of thickness-based biomarkers for clinical decision-making.

Cite This Study

Jabbehdari et al. (2026) studied this question.

synapsesocial.com/papers/69f19fd5edf4b46824806847https://doi.org/10.1177/11206721261445530
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Enhanced Depth Imaging Optical Coherence Tomography: Choroidal Thickness and Correlations With Age, Refractive Error, and Axial Length2012 · 64 citations
  2. 2Development of the retina and its relation with myopic shift varies from childhood to adolescence2021 · 19 citations
  3. 3Pre‐term delivery and subsequent ocular development1996 · 104 citations
  4. 4Multicenter Trial of Cryotherapy for Retinopathy of Prematurity1996 · 179 citations