Why the study?
Does measurement of cardiac troponin I (cTnI) provide higher specificity than MBCK for detecting myocardial injury in patients with skeletal muscle disease or renal failure?
Population
215 patients including 37 with acute skeletal muscle injury, 10 with chronic muscle disease, 9 marathon…
Comparison
Measurement of cardiac troponin I (cTnI) vs Measurement of MBCK
Design
Cross-sectional
Authors
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cTnI may offer higher specificity than MBCK for myocardial injury amid muscle disease or renal failure; hypothesis-generating, needing prospective validation.
Does measurement of cardiac troponin I (cTnI) provide higher specificity than MBCK for detecting myocardial injury in patients with skeletal muscle disease or renal failure?
Cardiac troponin I is highly specific for myocardial injury and can distinguish it from skeletal muscle injury or renal failure, unlike MBCK.
Adams et al. (1993) studied this question.
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