Why the study?
Does atrial systole influence the Frank-Starling relation and the end-diastolic pressure-diameter relation of the left ventricle?
Population
9 anesthetized, open-chest dogs whose atrioventricular (AV) node had been completely blocked
Comparison
AV sequential pacing during volume loading with… vs AV simultaneous pacing
Design
Preclinical
Authors
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Intact pericardium may enhance atrial contribution to LV performance in experimental models; leaves open human translation.
Does atrial systole influence the Frank-Starling relation and the end-diastolic pressure-diameter relation of the left ventricle?
In the presence of an intact pericardium, atrial systole improves left ventricular performance by increasing preload and shifting the end-diastolic pressure-diameter relation.
Linderer et al. (1983) studied this question.
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