Myocardial strain assessed by feature tracking cardiac magnetic resonance in patients with a variety of cardiovascular diseases – A comparison with echocardiography
Why the study?
It was unclear whether myocardial deformation analysis by feature tracking cardiac magnetic resonance and speckle tracking echocardiography could be used interchangeably across various cardiovascular diseases and healthy subjects.
Does feature tracking cardiac magnetic resonance (FT-CMR) provide interchangeable myocardial strain measurements compared to speckle tracking echocardiography (STE) in patients with cardiovascular diseases?
Population
40 patients with various cardiovascular diseases and 10 healthy subjects
Comparison
FT-CMR vs STE for myocardial deformation analysis
Design
Comparative imaging study
Authors
Discussion
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Member takes
Implication
FT-CMR and STE myocardial strains should not yet be used interchangeably; leaves open need for modality-specific references in cardiovascular disease.
Structured PICO
Does feature tracking cardiac magnetic resonance (FT-CMR) provide interchangeable myocardial strain measurements compared to speckle tracking echocardiography (STE) in patients with cardiovascular diseases?
P
Population
50 participants, including 40 patients with cardiovascular diseases (heart failure with reduced ejection fraction n=10, acute perimyocarditis n=10, aortic valve stenosis n=10, previous heart transplantation n=10) and 10 healthy subjects.
I
Intervention
Feature tracking cardiac magnetic resonance (FT-CMR) for myocardial deformation analysis (global longitudinal, radial, and circumferential strain)
C
Comparator
Speckle tracking echocardiography (STE)
O
Outcome
Correlation and agreement of global longitudinal (GLS), radial (GRS), and circumferential strain (GCS) between FT-CMR and STEsurrogate
Myocardial strain measurements by FT-CMR and STE show modest correlation but significant systematic bias, indicating the two modalities should not be used interchangeably in clinical practice.
Cite This Study
Pryds et al. (2019) studied this question.