Why the study?
Acute kidney injury occurring within 48 hours of major surgery may differ from acute kidney injury occurring after 48 hours in epidemiology, risk factors, and outcomes.
What are the risk factors and 1-year mortality outcomes associated with early versus late acute kidney injury in critically ill patients after noncardiac major surgery?
What are the risk factors and 1-year mortality outcomes associated with early versus late acute kidney injury in critically ill patients after noncardiac major surgery?
Early AKI after major noncardiac surgery is primarily associated with baseline patient factors, whereas late AKI is linked to postoperative complications, though both significantly increase 1-year mortality.
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AKI timing may inform etiology-specific risk assessment after noncardiac surgery; leaves open whether targeted prevention improves 1-year survival.
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Li et al. (2019) studied this question.
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