Demonstrates that altered electrophysiological properties and inducible repetitive activity can be found in the peripheral Purkinje system of idiopathic VF patients even without clinical short-coupled ectopy.
Ventricular ectopy mostly originating from the distal Purkinje system is observed in up to 30% of cases of idiopathic ventricular fibrillation (VF).1–5 These ectopies commonly have short coupling R-on-T intervals. However, the Purkinje triggers are often transient, present only during short arrhythmic periods, which prevents recognition of this condition and its treatment. Here, we report 2 patients with idiopathic VF in whom altered electrophysiological properties and inducible repetitive activity were demonstrated in the peripheral Purkinje system in the absence of clinical short-coupled ectopy.
Haı̈ssaguerre et al. (Wed,) studied this question.